Traditional, preclinical, emerging human, established human — four descriptions, used consistently.
- Author
- Akasha Editorial
- Reviewed by
- Akasha Review Board
- Published
- 2025-11-30
- Updated
- 2025-11-30
- Evidence reviewed
- 2025-11-30
Behind every ingredient page in this library is a single editorial field describing the strength of the evidence for that plant. We do not print it as a badge, because a badge invites the reader to skip the sentence that explains it. Instead, the wording of each page reflects it.
Traditional means a documented history of use with little modern research. Preclinical means laboratory or animal work exists but human studies do not, or are negligible. Emerging human evidence means controlled trials exist but are limited in number, size or consistency. Established human evidence means the human record is substantial and broadly consistent, often supported by regulatory monographs.
When an ingredient page reads cautiously, that is deliberate. It is what the record supports.
Referenced botanicals
References
- 01 Senna leaf: assessment report on Senna alexandrina. European Medicines Agency, EMA Herbal Monograph, 2018
- 02 Dietary Supplement Label Database. Office of Dietary Supplements, National Institutes of Health, 2024
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These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

